ABSTRACT
Objective To analyze the influence of Bushenjiangu Capsules on rheumatoid factor (RF), hypersensitive c-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR) with rheumatoid arthritis patients. Methods 94 patients with rheumatoid arthritis in the draw method was divided into control group and experimental group the 47 cases, control group treatmented by conventional western medicine, the experimental group based on the control group treatmented by Bushenjiangu Capsules, two groups' of RF, hs-CRP, ESR, Immunoglobulin A, M, G (IgA, IgM and IgG immune globulin), density lipoprotein (HDL-C), low density lipoprotein (LDL- C), triglyceride (TG), total cholesterol (TC), blood lipid, joint swelling, joint tenderness, morning stiffness time, curative effect and adverse reactions were compared. Results After treatmented, the RF, hs-CRP, ESR of experimental group was lower than the control group (57.53±8.13) U/L, (6.30±0.78) mg/L, (21.48±3.03) mm/h vs (74.29±10.56) U/L, (13.14±1.86 )mg/L, (35.60±4.36) mm/h, the difference was statistically significant (P<0.05). The IgA, IgM and IgG, HDL, LDL - C - C, TG, TC, joint swelling count, joint tenderness, morning stiffness time of experimental group was better than control group (2.17±0.29) g/L, (1.53±0.21) g/L, (12.14±1.50) g/L, (1.25±0.15)mmol/L (2.11 ±0.26) mmol/L, (1.34±0.17) mmol/L, (4.03±0.50) mmol/L, (4.35±0.53), (6.30±0.77), (29.71±3.70) min than g/L (2.30±0.28), (2.11±0.26) g/L, (13.76±1.70) g/L, (1.16±0.14) mmol/L (2.29±0.28) mmol/L, (1.53±0.19) mmol/L, (4.50±0.55) mmol/L, (7.63±0.96), (8.51±1.21), (76.38±9.50) min (P<0.05). The total effective rate of experimental group was higher than the control group (93.61%vs 76.59%) (P<0.05).The adverse reaction of two groups was no difference. Conclusion The effect is sure of Bushenjiangu capsule treatment of rheumatoid arthritis, can reduce the levels of RF, hs-CRP, ESR.
ABSTRACT
Objective: By building database model, to put forward measures to solve the shortage of basic drugs. Methods: There were five factors influencing medicine shortage have been researched, collecting data, using SPSS 18.0 software to build the database model of different parts, and then analyzed the existing problems and inner link, scientifically came up with the basic framework and main solutions of guarantee measures on shortages of essential medicines. Results: The database model of country and six areas in it have been built, and the influence factors of drug shortage in different region have been analyzed, and raised five aspects measures to secure reliable supplies of drugs, including selection, bid and procurement; production and flow; reserve and adjust;pricing and pay;use training. Conclusion: This study extends the application of database, enriches research ideas of drug policy, and the policy put forward to avoid drug shortages to a certain extent.